Reproducibility of Reported Cell Line Identities: A Case Study of Authentication in Published Work

Authors

  • Demetris Charilaou Department of Cell Biology, Pentadaktylos Centre for Molecular Life Sciences, Lefkara, Cyprus Author
  • Bard Dalsbotten Centre for Research Practice, Setesdal Institute of Biological Sciences, Evje, Norway Author
  • Birute-M Aleksandravicius Centre for Research Ethics, Kursiu Institute of Biological Sciences, Neringa, Lithuania Author

DOI:

https://doi.org/10.5281/zenodo.22667429

Keywords:

Reproducibility of Reported Cell Line Identities; Biological sciences; Evidence synthesis; Reproducibility; Research methodology

Abstract

There is real interest in reproducibility of reported cell line identities right now, and real uncertainty about exactly where it
delivers the most value. We pull together the current evidence for reproducibility of reported cell line identities, covering the
methodological, practical, regulatory and cost angles, with an eye on where practice has genuinely settled and where researchers
and reviewers are still largely working it out for themselves. Selective, context-specific adoption looks better supported by the
evidence gathered here than either broad rollout or blanket avoidance.

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Published

2023-12-30