Antibiotic Resistance Gene Flow Between Environmental and Clinical Reservoirs: A One Health Review

Authors

  • Leandro Sagramoso Centre for One Health, Cadore Institute of Biological Sciences, Pieve di Cadore, Italy Author
  • Endel Bachmann Department of Microbial Ecology, Saaremaa Institute of Biological Sciences, Kuressaare, Estonia Author
  • Freerk Leeuwenburgh Centre for Disease Ecology, Gooi Institute of Biological Sciences, Hilversum, Netherlands Author

DOI:

https://doi.org/10.5281/zenodo.22668476

Keywords:

Antibiotic Resistance Gene Flow Between Environmental and Clinical Reservoirs; Biological sciences; Evidence synthesis; Reproducibility; Research methodology

Abstract

There is real interest in antibiotic resistance gene flow between environmental and clinical reservoirs right now, and real
uncertainty about exactly where it delivers the most value. We pull together the current evidence for antibiotic resistance gene
flow between environmental and clinical reservoirs, covering the methodological, practical, regulatory and cost angles, with an
eye on where practice has genuinely settled and where researchers and reviewers are still largely working it out for themselves.
Selective, context-specific adoption looks better supported by the evidence gathered here than either broad rollout or blanket
avoidance.

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Published

2025-07-19