Immune Memory in Invertebrates: A Review of Evidence for Specificity and Its Mechanisms

Authors

  • Hortensia-M Fombellida Department of Immunology, Guadalhorce Centre for Molecular Life Sciences, Alora, Spain Author
  • Gediminas Ereminas Department of Evolutionary Biology, Kursiu Institute of Biological Sciences, Neringa, Lithuania Author
  • Gustav-M Immonen Department of Entomology, Aland Centre for Molecular Life Sciences, Mariehamn, Finland Author

DOI:

https://doi.org/10.5281/zenodo.22668567

Keywords:

Immune Memory in Invertebrates; Biological sciences; Evidence synthesis; Reproducibility; Research methodology

Abstract

Immune Memory in Invertebrates has moved quickly from a niche research question to something a wider community can now
investigate with reasonably reliable tools, but the evidence behind it has not always kept pace. We pull together the current
evidence for immune memory in invertebrates, covering the methodological, practical, regulatory and cost angles, with an eye on
where practice has genuinely settled and where researchers and reviewers are still largely working it out for themselves. Selective,
context-specific adoption looks better supported by the evidence gathered here than either broad rollout or blanket avoidance.

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Published

2025-10-19