Xenotransplantation Reaches the Clinic: Immunological Barriers and the Consent Problem
DOI:
https://doi.org/10.5281/zenodo.22649242Keywords:
Xenotransplantation Reaches the Clinic; Translational medicine, Evidence synthesis; Clinical implementation;, Health services researchAbstract
Xenotransplantation Reaches the Clinic is an area of active development in translational medicine, with evidence that has
accumulated unevenly across its component questions. We review the current evidence base for xenotransplantation reaches the
clinic, spanning analytical, clinical, implementation, governance, and economic dimensions, focusing on where practice has
converged and where it continues to vary, and set out the practical considerations relevant to a service considering its adoption.
We conclude that selective, context-specific use is best supported by the evidence currently available, rather than uniform
adoption or avoidance.
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