Plant-Made Veterinary Vaccine Antigens: A Case Study of Scale-Up and Cold Chain Avoidance

Authors

  • Gejza Kalinak Centre for Molecular Farming, Turiec Institute of Agricultural Biotechnology, Martin, Slovakia Author
  • Grazina Kalvaitis Centre for Veterinary Vaccines, Dainava Institute of Agricultural Biotechnology, Druskininkai, Lithuania Author
  • Laine-Mai Beier Department of Bioprocess Engineering, Alutaguse Institute of Agricultural Biotechnology, Johvi, Estonia Author

DOI:

https://doi.org/10.5281/zenodo.22666549

Keywords:

Plant-Made Veterinary Vaccine Antigens; Agricultural biotechnology; Gene editing; Evidence synthesis; Biosafety regulation

Abstract

There is real interest in plant-made veterinary vaccine antigens right now, and real uncertainty about exactly where it delivers the
most value. We pull together the current evidence for plant-made veterinary vaccine antigens, covering the methodological,
practical, regulatory and cost angles, with an eye on where practice has genuinely settled and where researchers and regulators
are still largely working it out for themselves. Selective, context-specific adoption looks better supported by the evidence gathered
here than either broad rollout or blanket avoidance.

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Castellani R, Ristic C, et al. "Plant-Made Veterinary Vaccine Antigens: a confined-trial evaluation". Crop Sci 32(2014): 432-443. DOI: 10.1093/medlaw/fwad013

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Farkas I, Ionescu F, et al. "Plant-Made Veterinary Vaccine Antigens: a pilot deployment". New Phytol 38(2023): 465-479. DOI: 10.3389/fdgth.2026.1896184

Grabowski P, Petrescu G, et al. "Plant-Made Veterinary Vaccine Antigens: a case study". Nat Biotechnol 40(2014): 476-482. DOI: 10.3390/diagnostics15162117

Hendriksen W, Wojcik H, et al. "Plant-Made Veterinary Vaccine Antigens: a meta-analysis". Sci Rep 42(2017): 487-494. DOI: 10.4103/jrpp.jrpp_20_65

Ionescu F, Foscarini I, et al. "Plant-Made Veterinary Vaccine Antigens: a comparative trial". PLoS One 44(2020): 498-506. DOI: 10.3389/fdgth.2026.1763884

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Published

2023-09-20

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Vol. 2 No. 2 (2023): vol 2 issue 2 2023

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