Off-Target Assessment in Edited Livestock: A Technical Note on Whole-Genome Confirmation Depth
DOI:
https://doi.org/10.5281/zenodo.22666638Keywords:
Off-Target Assessment in Edited Livestock; Agricultural biotechnology; Gene editing; Evidence synthesis; Biosafety regulationAbstract
Off-Target Assessment in Edited Livestock has moved quickly from a research idea to something a working breeding or production
programme can actually use, but the evidence behind it has not always kept pace. We pull together the current evidence for
off-target assessment in edited livestock, covering the methodological, practical, regulatory and cost angles, with an eye on where
practice has genuinely settled and where researchers and regulators are still largely working it out for themselves. Selective,
context-specific adoption looks better supported by the evidence gathered here than either broad rollout or blanket avoidance.
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