Recombinant Enzyme Production in Filamentous Fungi: A Case Study of Strain Instability at Scale

Abstract

Recombinant Enzyme Production in Filamentous Fungi has moved quickly from a research idea to something a working breeding
or production programme can actually use, but the evidence behind it has not always kept pace. We pull together the current
evidence for recombinant enzyme production in filamentous fungi, covering the methodological, practical, regulatory and cost
angles, with an eye on where practice has genuinely settled and where researchers and regulators are still largely working it out
for themselves. Selective, context-specific adoption looks better supported by the evidence gathered here than either broad rollout
or blanket avoidance.