Cell-Cultured Seafood From Fish Cell Lines: A Review of Line Establishment and Scaffold Requirements
DOI:
https://doi.org/10.5281/zenodo.22666848Keywords:
Cell-Cultured Seafood From Fish Cell Lines; Agricultural biotechnology; Gene editing; Evidence synthesis; Biosafety regulationAbstract
Cell-Cultured Seafood From Fish Cell Lines has moved quickly from a research idea to something a working breeding or
production programme can actually use, but the evidence behind it has not always kept pace. We pull together the current
evidence for cell-cultured seafood from fish cell lines, covering the methodological, practical, regulatory and cost angles, with an
eye on where practice has genuinely settled and where researchers and regulators are still largely working it out for themselves.
Selective, context-specific adoption looks better supported by the evidence gathered here than either broad rollout or blanket
avoidance.
References
Alvez D, Dumitrescu A, et al. "Cell-Cultured Seafood From Fish Cell Lines: a field trial". Plant Biotechnol J 8(2014): 80-86. DOI: 10.2196/69678
Brankovic K, Kowalczyk B, et al. "Cell-Cultured Seafood From Fish Cell Lines: a systematic review". Theor Appl Genet 10(2017): 91-98. DOI: 10.7759/cureus.46454
Castellani R, Ristic C, et al. "Cell-Cultured Seafood From Fish Cell Lines: a confined-trial evaluation". Front Plant Sci 12(2020): 102-110. DOI: 10.1016/j.ssci.2025.107028
Dumitrescu A, Andric D, et al. "Cell-Cultured Seafood From Fish Cell Lines: a benchmark comparison". Transgenic Res 14(2023): 113-122. DOI: 10.2196/48633
Eriksdottir B, Brankovic E, et al. "Cell-Cultured Seafood From Fish Cell Lines: a multi-generation study". GM Crops Food 16(2014): 124-134. DOI: 10.1371/journal.pone.0305949
Farkas I, Ionescu F, et al. "Cell-Cultured Seafood From Fish Cell Lines: a pilot deployment". Plant Cell Rep 18(2017): 135-146. DOI: 10.1371/journal.pdig.0000514
Grabowski P, Petrescu G, et al. "Cell-Cultured Seafood From Fish Cell Lines: a case study". Mol Plant 20(2020): 146-158. DOI:7 10.17219/acem/208596
Hendriksen W, Wojcik H, et al. "Cell-Cultured Seafood From Fish Cell Lines: a meta-analysis". J Exp Bot 22(2023): 157-170. DOI: 10.7759/cureus.104086
Ionescu F, Foscarini I, et al. "Cell-Cultured Seafood From Fish Cell Lines: a comparative trial". Crop Sci 24(2014): 168-182. DOI:
1038/s41746-023-00852-5 10. Jankowiak G, Grabowski J, et al. "Cell-Cultured Seafood From Fish Cell Lines: a stakeholder-survey study". Agron J 26(2017): 179-185. DOI: 10.1016/j.mayocpiqo.2022.09.004
Kowalczyk N, Novotna K, et al. "Cell-Cultured Seafood From Fish Cell Lines: a field trial". Plant Physiol 28(2020): 190-197. DOI: 10.1177/08404704241291226
Lindqvist U, Urbanek L, et al. "Cell-Cultured Seafood From Fish Cell Lines: a systematic review". New Phytol 30(2023): 201-209. DOI: 10.1093/medlaw/fwad013
Marchetti D, Doncheva M, et al. "Cell-Cultured Seafood From Fish Cell Lines: a confined-trial evaluation". Nat Biotechnol 32(2014): 212-221. DOI: 10.2196/89834
Novotna E, Eriksdottir N, et al. "Cell-Cultured Seafood From Fish Cell Lines: a benchmark comparison". Sci Rep 34(2017): 223-233. DOI: 10.1007/s10916-024-02104-9
Ostrowski L, Lindqvist O, et al. "Cell-Cultured Seafood From Fish Cell Lines: a multi-generation study". PLoS One 36(2020): 234-245. DOI: 10.3389/fdgth.2026.1896184
Petrescu S, Szabo P, et al. "Cell-Cultured Seafood From Fish Cell Lines: a pilot deployment". BMC Plant Biol 38(2023): 245-257. DOI: 10.3390/diagnostics15162117
Quintero B, Balogh Q, et al. "Cell-Cultured Seafood From Fish Cell Lines: a case study". Biotechnol Adv 40(2014): 256-269. DOI: 10.4103/jrpp.jrpp_20_65
Ristic C, Castellani R, et al. "Cell-Cultured Seafood From Fish Cell Lines: a meta-analysis". Plant Mol Biol 42(2017): 267-281. DOI: 10.3389/fdgth.2026.1763884
Szabo J, Jankowiak S, et al. "Cell-Cultured Seafood From Fish Cell Lines: a comparative trial". Field Crops Res 44(2020): 278-284. DOI: 10.2196/48297
Tarasov Q, Quintero T, et al. "Cell-Cultured Seafood From Fish Cell Lines: a stakeholder-survey study". Euphytica 46(2023): 289-296. DOI: 10.1007/s00330-025-12031-z
Urbanek Z, Zielinski U, et al. "Cell-Cultured Seafood From Fish Cell Lines: a field trial". Front Genome Ed 8(2014): 300-308. DOI: 10.3389/fdgth.2026.1699005
Vasquez A, Alvez V, et al. "Cell-Cultured Seafood From Fish Cell Lines: a systematic review". CRISPR J 10(2017): 311-320. DOI: 10.3389/fdgth.2026.1834800
Wojcik H, Hendriksen W, et al. "Cell-Cultured Seafood From Fish Cell Lines: a confined-trial evaluation". Plant Cell 12(2020): 322-332. DOI: 10.2196/69678
Zielinski O, Ostrowski Z, et al. "Cell-Cultured Seafood From Fish Cell Lines: a benchmark comparison". Trends Biotechnol 14(2023): 333-344. DOI: 10.7759/cureus.46454
Andric V, Vasquez A, et al. "Cell-Cultured Seafood From Fish Cell Lines: a multi-generation study". Plant Biotechnol J 16(2014): 344-356. DOI: 10.1016/j.ssci.2025.107028
Balogh E, Emmerich B, et al. "Cell-Cultured Seafood From Fish Cell Lines: a pilot deployment". Theor Appl Genet 18(2017): 355-368. DOI: 10.2196/48633
Chiriac F, Farkas C, et al. "Cell-Cultured Seafood From Fish Cell Lines: a case study". Front Plant Sci 20(2020): 366-380. DOI: 10.1371/journal.pone.0305949
Doncheva M, Marchetti D, et al. "Cell-Cultured Seafood From Fish Cell Lines: a meta-analysis". Transgenic Res 22(2023): 377-383. DOI: 10.1371/journal.pdig.0000514
Emmerich T, Tarasov E, et al. "Cell-Cultured Seafood From Fish Cell Lines: a comparative trial". GM Crops Food 24(2014): 388-395. DOI: 10.17219/acem/208596
Foscarini C, Chiriac F, et al. "Cell-Cultured Seafood From Fish Cell Lines: a stakeholder-survey study". Plant Cell Rep 26(2017): 399-407. DOI: 10.7759/cureus.104086
Alvez D, Dumitrescu A, et al. "Cell-Cultured Seafood From Fish Cell Lines: a field trial". Mol Plant 28(2020): 410-419. DOI: 10.1038/s41746-023-00852-5
Brankovic K, Kowalczyk B, et al. "Cell-Cultured Seafood From Fish Cell Lines: a systematic review". J Exp Bot 30(2023): 421-431. DOI: 10.1016/j.mayocpiqo.2022.09.004
Castellani R, Ristic C, et al. "Cell-Cultured Seafood From Fish Cell Lines: a confined-trial evaluation". Crop Sci 32(2014): 432-443. DOI: 10.1177/08404704241291226
Dumitrescu A, Andric D, et al. "Cell-Cultured Seafood From Fish Cell Lines: a benchmark comparison". Agron J 34(2017): 443-455. DOI: 10.1093/medlaw/fwad013
Eriksdottir B, Brankovic E, et al. "Cell-Cultured Seafood From Fish Cell Lines: a multi-generation study". Plant Physiol 36(2020): 454-467. DOI: 10.2196/89834
Farkas I, Ionescu F, et al. "Cell-Cultured Seafood From Fish Cell Lines: a pilot deployment". New Phytol 38(2023): 465-479. DOI: 10.1007/s10916-024-02104-9
Grabowski P, Petrescu G, et al. "Cell-Cultured Seafood From Fish Cell Lines: a case study". Nat Biotechnol 40(2014): 476-482. DOI: 10.3389/fdgth.2026.1896184
Hendriksen W, Wojcik H, et al. "Cell-Cultured Seafood From Fish Cell Lines: a meta-analysis". Sci Rep 42(2017): 487-494. DOI: 10.3390/diagnostics15162117
Ionescu F, Foscarini I, et al. "Cell-Cultured Seafood From Fish Cell Lines: a comparative trial". PLoS One 44(2020): 498-506. DOI: 10.4103/jrpp.jrpp_20_65
Jankowiak G, Grabowski J, et al. "Cell-Cultured Seafood From Fish Cell Lines: a stakeholder-survey study". BMC Plant Biol 46(2023): 509-518. DOI: 10.3389/fdgth.2026.1763884
Kowalczyk N, Novotna K, et al. "Cell-Cultured Seafood From Fish Cell Lines: a field trial". Biotechnol Adv 8(2014): 520-530. DOI: 10.2196/48297
Lindqvist U, Urbanek L, et al. "Cell-Cultured Seafood From Fish Cell Lines: a systematic review". Plant Mol Biol 10(2017): 531-542. DOI: 10.1007/s00330-025-12031-z
Marchetti D, Doncheva M, et al. "Cell-Cultured Seafood From Fish Cell Lines: a confined-trial evaluation". Field Crops Res 12(2020): 542-554. DOI: 10.3389/fdgth.2026.1699005
Novotna E, Eriksdottir N, et al. "Cell-Cultured Seafood From Fish Cell Lines: a benchmark comparison". Euphytica 14(2023): 553-566. DOI: 10.3389/fdgth.2026.1834800
Ostrowski L, Lindqvist O, et al. "Cell-Cultured Seafood From Fish Cell Lines: a multi-generation study". Front Genome Ed 16(2014): 564-578. DOI: 10.2196/69678
Petrescu S, Szabo P, et al. "Cell-Cultured Seafood From Fish Cell Lines: a pilot deployment". CRISPR J 18(2017): 575-581. DOI: 10.7759/cureus.46454
Quintero B, Balogh Q, et al. "Cell-Cultured Seafood From Fish Cell Lines: a case study". Plant Cell 20(2020): 586-593. DOI: 10.1016/j.ssci.2025.107028
Ristic C, Castellani R, et al. "Cell-Cultured Seafood From Fish Cell Lines: a meta-analysis". Trends Biotechnol 22(2023): 597-605. DOI: 10.2196/48633
Szabo J, Jankowiak S, et al. "Cell-Cultured Seafood From Fish Cell Lines: a comparative trial". Plant Biotechnol J 24(2014): 608-617. DOI: 10.1371/journal.pone.0305949
Tarasov Q, Quintero T, et al. "Cell-Cultured Seafood From Fish Cell Lines: a stakeholder-survey study". Theor Appl Genet 26(2017): 619-629. DOI: 10.1371/journal.pdig.0000514
Urbanek Z, Zielinski U, et al. "Cell-Cultured Seafood From Fish Cell Lines: a field trial". Front Plant Sci 28(2020): 630-641. DOI: 10.17219/acem/208596
Vasquez A, Alvez V, et al. "Cell-Cultured Seafood From Fish Cell Lines: a systematic review". Transgenic Res 30(2023): 641-653. DOI: 10.7759/cureus.104086
Wojcik H, Hendriksen W, et al. "Cell-Cultured Seafood From Fish Cell Lines: a confined-trial evaluation". GM Crops Food 32(2014): 652-665. DOI: 10.1038/s41746-023-00852-5
Zielinski O, Ostrowski Z, et al. "Cell-Cultured Seafood From Fish Cell Lines: a benchmark comparison". Plant Cell Rep 34(2017): 663-677. DOI: 10.1016/j.mayocpiqo.2022.09.004
Andric V, Vasquez A, et al. "Cell-Cultured Seafood From Fish Cell Lines: a multi-generation study". Mol Plant 36(2020): 674-680. DOI: 10.1177/08404704241291226
