Automated Liquid Handling for Reproducible Cell Assays: A Technical Note on Error Sources

Authors

  • Hynek Erben Department of Laboratory Automation, Ceskolipsko Institute of Biological Sciences, Ceska Lipa, Czech Republic Author
  • Lauri-Matti Laurila Department of Cell Biology, Aland Centre for Molecular Life Sciences, Mariehamn, Finland Author
  • Gudny Larusson Department of Biostatistics, Vestmannaeyjar Institute of Biological Sciences, Heimaey, Iceland Author

DOI:

https://doi.org/10.5281/zenodo.22667265

Keywords:

Automated Liquid Handling for Reproducible Cell Assays; Biological sciences; Evidence synthesis; Reproducibility; Research methodology

Abstract

There is real interest in automated liquid handling for reproducible cell assays right now, and real uncertainty about exactly
where it delivers the most value. We pull together the current evidence for automated liquid handling for reproducible cell assays,
covering the methodological, practical, regulatory and cost angles, with an eye on where practice has genuinely settled and where
researchers and reviewers are still largely working it out for themselves. Selective, context-specific adoption looks better
supported by the evidence gathered here than either broad rollout or blanket avoidance

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Published

2022-11-15