Sample Provenance in Multi-Site Studies: A Technical Note on Chain-of-Custody Metadata

Authors

  • Lucien Hauteclaire Department of Biobanking, Dombes Laboratory for Ecology and Evolution, Villars-les-Dombes, France Author
  • Philippa Trescothick Centre for Research Practice, Arran Laboratory for Ecology and Evolution, Brodick, United Kingdom Author
  • Ilona-M Erdos-Bak Department of Bioinformatics, Bukk Institute of Biological Sciences, Miskolc, Hungary Author

DOI:

https://doi.org/10.5281/zenodo.22667345

Keywords:

Sample Provenance in Multi-Site Studies; Biological sciences; Evidence synthesis; Reproducibility; Research methodology

Abstract

Sample Provenance in Multi-Site Studies has moved quickly from a niche research question to something a wider community can
now investigate with reasonably reliable tools, but the evidence behind it has not always kept pace. We pull together the current
evidence for sample provenance in multi-site studies, covering the methodological, practical, regulatory and cost angles, with an
eye on where practice has genuinely settled and where researchers and reviewers are still largely working it out for themselves.
Selective, context-specific adoption looks better supported by the evidence gathered here than either broad rollout or blanket
avoidance.

References

Alvez D, Dumitrescu A, et al. "Sample Provenance in Multi-Site Studies: a observational study". Nature 8(2014): 80-86. DOI: 10.7759/cureus.46454

Brankovic K, Kowalczyk B, et al. "Sample Provenance in Multi-Site Studies: a systematic review". Science 10(2017): 91-98. DOI: 10.1016/j.ssci.2025.107028

Castellani R, Ristic C, et al. "Sample Provenance in Multi-Site Studies: a comparative analysis". PNAS 12(2020): 102-110. DOI: 10.2196/48633

Dumitrescu A, Andric D, et al. "Sample Provenance in Multi-Site Studies: a benchmark comparison". Cell 14(2023): 113-122. DOI: 10.1371/journal.pone.0305949

Eriksdottir B, Brankovic E, et al. "Sample Provenance in Multi-Site Studies: a longitudinal study". eLife 16(2014): 124-134. DOI: 10.1371/journal.pdig.0000514 7

Farkas I, Ionescu F, et al. "Sample Provenance in Multi-Site Studies: a pilot investigation". PLoS Biology 18(2017): 135-146. DOI: 10.17219/acem/208596

Grabowski P, Petrescu G, et al. "Sample Provenance in Multi-Site Studies: a case study". Nature Communications 20(2020): 146-158. DOI: 10.7759/cureus.104086

Hendriksen W, Wojcik H, et al. "Sample Provenance in Multi-Site Studies: a meta-analysis". Current Biology 22(2023): 157-170. DOI: 10.1038/s41746-023-00852-5

Ionescu F, Foscarini I, et al. "Sample Provenance in Multi-Site Studies: a cross-sectional survey". Nature Ecology & Evolution 24(2014): 168-182. DOI: 10.1016/j.mayocpiqo.2022.09.004

Jankowiak G, Grabowski J, et al. "Sample Provenance in Multi-Site Studies: a methods-comparison study". Molecular Biology and Evolution 26(2017): 179-185. DOI: 10.1177/08404704241291226

Kowalczyk N, Novotna K, et al. "Sample Provenance in Multi-Site Studies: a observational study". Genome Biology 28(2020): 190-197. DOI: 10.1093/medlaw/fwad013

Lindqvist U, Urbanek L, et al. "Sample Provenance in Multi-Site Studies: a systematic review". Nature Methods 30(2023): 201-209. DOI: 10.2196/89834

Marchetti D, Doncheva M, et al. "Sample Provenance in Multi-Site Studies: a comparative analysis". BMC Biology 32(2014): 212-221. DOI: 10.1007/s10916-024-02104-9

Novotna E, Eriksdottir N, et al. "Sample Provenance in Multi-Site Studies: a benchmark comparison". Journal of Experimental Biology 34(2017): 223-233. DOI: 10.3389/fdgth.2026.1896184

Ostrowski L, Lindqvist O, et al. "Sample Provenance in Multi-Site Studies: a longitudinal study". Ecology Letters 36(2020): 234-245. DOI: 10.3390/diagnostics15162117

Petrescu S, Szabo P, et al. "Sample Provenance in Multi-Site Studies: a pilot investigation". Conservation Biology 38(2023): 245-257. DOI: 10.4103/jrpp.jrpp_20_65

Quintero B, Balogh Q, et al. "Sample Provenance in Multi-Site Studies: a case study". Trends in Ecology & Evolution 40(2014): 256-269. DOI: 10.3389/fdgth.2026.1763884

Ristic C, Castellani R, et al. "Sample Provenance in Multi-Site Studies: a meta-analysis". Cell Reports 42(2017): 267-281. DOI: 10.2196/48297

Szabo J, Jankowiak S, et al. "Sample Provenance in Multi-Site Studies: a cross-sectional survey". Nature Microbiology 44(2020): 278-284. DOI: 10.1007/s00330-025-12031-z

Tarasov Q, Quintero T, et al. "Sample Provenance in Multi-Site Studies: a methods-comparison study". Molecular Ecology 46(2023): 289-296. DOI: 10.3389/fdgth.2026.1699005

Urbanek Z, Zielinski U, et al. "Sample Provenance in Multi-Site Studies: a observational study". Scientific Reports 8(2014): 300-308. DOI: 10.3389/fdgth.2026.1834800

Vasquez A, Alvez V, et al. "Sample Provenance in Multi-Site Studies: a systematic review". Proceedings of the Royal Society B 10(2017): 311-320. DOI: 10.2196/69678

Wojcik H, Hendriksen W, et al. "Sample Provenance in Multi-Site Studies: a comparative analysis". Journal of Cell Biology 12(2020): 322-332. DOI: 10.7759/cureus.46454

Zielinski O, Ostrowski Z, et al. "Sample Provenance in Multi-Site Studies: a benchmark comparison". Trends in Cell Biology 14(2023): 333-344. DOI: 10.1016/j.ssci.2025.107028

Andric V, Vasquez A, et al. "Sample Provenance in Multi-Site Studies: a longitudinal study". Nature Biotechnology 16(2014): 344-356. DOI: 10.2196/48633

Balogh E, Emmerich B, et al. "Sample Provenance in Multi-Site Studies: a pilot investigation". Nature 18(2017): 355-368. DOI: 10.1371/journal.pone.0305949

Chiriac F, Farkas C, et al. "Sample Provenance in Multi-Site Studies: a case study". Science 20(2020): 366-380. DOI: 10.1371/journal.pdig.0000514

Doncheva M, Marchetti D, et al. "Sample Provenance in Multi-Site Studies: a meta-analysis". PNAS 22(2023): 377-383. DOI: 10.17219/acem/208596

Emmerich T, Tarasov E, et al. "Sample Provenance in Multi-Site Studies: a cross-sectional survey". Cell 24(2014): 388-395. DOI: 10.7759/cureus.104086

Foscarini C, Chiriac F, et al. "Sample Provenance in Multi-Site Studies: a methods-comparison study". eLife 26(2017): 399-407. DOI: 10.1038/s41746-023-00852-5

Alvez D, Dumitrescu A, et al. "Sample Provenance in Multi-Site Studies: a observational study". PLoS Biology 28(2020): 410-419. DOI: 10.1016/j.mayocpiqo.2022.09.004

Brankovic K, Kowalczyk B, et al. "Sample Provenance in Multi-Site Studies: a systematic review". Nature Communications 30(2023): 421-431. DOI: 10.1177/08404704241291226

Castellani R, Ristic C, et al. "Sample Provenance in Multi-Site Studies: a comparative analysis". Current Biology 32(2014): 432-443. DOI: 10.1093/medlaw/fwad013

Dumitrescu A, Andric D, et al. "Sample Provenance in Multi-Site Studies: a benchmark comparison". Nature Ecology & Evolution 34(2017): 443-455. DOI: 10.2196/89834

Eriksdottir B, Brankovic E, et al. "Sample Provenance in Multi-Site Studies: a longitudinal study". Molecular Biology and Evolution 36(2020): 454-467. DOI: 10.1007/s10916-024-02104-9

Farkas I, Ionescu F, et al. "Sample Provenance in Multi-Site Studies: a pilot investigation". Genome Biology 38(2023): 465-479. DOI: 10.3389/fdgth.2026.1896184

Grabowski P, Petrescu G, et al. "Sample Provenance in Multi-Site Studies: a case study". Nature Methods 40(2014): 476-482. DOI: 10.3390/diagnostics15162117

Hendriksen W, Wojcik H, et al. "Sample Provenance in Multi-Site Studies: a meta-analysis". BMC Biology 42(2017): 487-494. DOI: 10.4103/jrpp.jrpp_20_65

Ionescu F, Foscarini I, et al. "Sample Provenance in Multi-Site Studies: a cross-sectional survey". Journal of Experimental Biology 44(2020): 498-506. DOI: 10.3389/fdgth.2026.1763884

Jankowiak G, Grabowski J, et al. "Sample Provenance in Multi-Site Studies: a methods-comparison study". Ecology Letters 46(2023): 509-518. DOI: 10.2196/48297

Kowalczyk N, Novotna K, et al. "Sample Provenance in Multi-Site Studies: a observational study". Conservation Biology 8(2014): 520-530. DOI: 10.1007/s00330-025-12031-z

Lindqvist U, Urbanek L, et al. "Sample Provenance in Multi-Site Studies: a systematic review". Trends in Ecology & Evolution 10(2017): 531-542. DOI: 10.3389/fdgth.2026.1699005

Marchetti D, Doncheva M, et al. "Sample Provenance in Multi-Site Studies: a comparative analysis". Cell Reports 12(2020): 542-554. DOI: 10.3389/fdgth.2026.1834800

Novotna E, Eriksdottir N, et al. "Sample Provenance in Multi-Site Studies: a benchmark comparison". Nature Microbiology 14(2023): 553-566. DOI: 10.2196/69678

Ostrowski L, Lindqvist O, et al. "Sample Provenance in Multi-Site Studies: a longitudinal study". Molecular Ecology 16(2014): 564-578. DOI: 10.7759/cureus.46454

Petrescu S, Szabo P, et al. "Sample Provenance in Multi-Site Studies: a pilot investigation". Scientific Reports 18(2017): 575-581. DOI: 10.1016/j.ssci.2025.107028

Quintero B, Balogh Q, et al. "Sample Provenance in Multi-Site Studies: a case study". Proceedings of the Royal Society B 20(2020): 586-593. DOI: 10.2196/48633

Ristic C, Castellani R, et al. "Sample Provenance in Multi-Site Studies: a meta-analysis". Journal of Cell Biology 22(2023): 597-605. DOI: 10.1371/journal.pone.0305949

Szabo J, Jankowiak S, et al. "Sample Provenance in Multi-Site Studies: a cross-sectional survey". Trends in Cell Biology 24(2014): 608-617. DOI: 10.1371/journal.pdig.0000514

Tarasov Q, Quintero T, et al. "Sample Provenance in Multi-Site Studies: a methods-comparison study". Nature Biotechnology 26(2017): 619-629. DOI: 10.17219/acem/208596

Urbanek Z, Zielinski U, et al. "Sample Provenance in Multi-Site Studies: a observational study". Nature 28(2020): 630-641. DOI: 10.7759/cureus.104086

Vasquez A, Alvez V, et al. "Sample Provenance in Multi-Site Studies: a systematic review". Science 30(2023): 641-653. DOI: 10.1038/s41746-023-00852-5

Wojcik H, Hendriksen W, et al. "Sample Provenance in Multi-Site Studies: a comparative analysis". PNAS 32(2014): 652-665. DOI: 10.1016/j.mayocpiqo.2022.09.004

Zielinski O, Ostrowski Z, et al. "Sample Provenance in Multi-Site Studies: a benchmark comparison". Cell 34(2017): 663-677. DOI: 10.1177/08404704241291226

Andric V, Vasquez A, et al. "Sample Provenance in Multi-Site Studies: a longitudinal study". eLife 36(2020): 674-680. DOI: 10.1093/medlaw/fwad013

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Published

2023-06-19

Issue

Vol. 2 No. 1 (2023): Vol 2 Issue 1 2023

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