Epigenetic Clocks in Non-Human Species: A Systematic Review of Calibration and Transferability

Authors

  • Erika Kuhnis Department of Epigenetics, Entlebuch Institute of Biological Sciences, Schupfheim, Switzerland Author
  • Ligia Ganea Centre for Ageing Research, Danube Delta Centre for Molecular Life Sciences, Tulcea, Romania Author
  • Jelena-S Ilijin Department of Biostatistics, Homolje Institute of Biological Sciences, Petrovac, Serbia Author

DOI:

https://doi.org/10.5281/zenodo.22667394

Keywords:

Epigenetic Clocks in Non-Human Species; Biological sciences; Evidence synthesis; Reproducibility; Research methodology

Abstract

Epigenetic Clocks in Non-Human Species has moved quickly from a niche research question to something a wider community can
now investigate with reasonably reliable tools, but the evidence behind it has not always kept pace. We pull together the current
evidence for epigenetic clocks in non-human species, covering the methodological, practical, regulatory and cost angles, with an
eye on where practice has genuinely settled and where researchers and reviewers are still largely working it out for themselves.
Selective, context-specific adoption looks better supported by the evidence gathered here than either broad rollout or blanket
avoidance.

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Published

2023-09-29

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Vol. 2 No. 2 (2023): Vol 2 Issue 2 2023

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