Neural Circuit Mapping With Activity-Dependent Labelling: A Benchmark of Three Reporter Systems

Abstract

Neural Circuit Mapping With Activity-Dependent Labelling has moved quickly from a niche research question to something a
wider community can now investigate with reasonably reliable tools, but the evidence behind it has not always kept pace. We pull
together the current evidence for neural circuit mapping with activity-dependent labelling, covering the methodological, practical,
regulatory and cost angles, with an eye on where practice has genuinely settled and where researchers and reviewers are still
largely working it out for themselves. Selective, context-specific adoption looks better supported by the evidence gathered here
than either broad rollout or blanket avoidance.