Longevity Interventions in Model Systems: Systematic Review of Effect Size Against Reporting Quality

Authors

  • Arnljot Aarnes Centre for Longevity Research, Dovre Institute for Future Science, Dombas, Norway Author
  • Fokeltje Hoogenboezem Department of Statistical Methods, Wadden Institute for Future Science, Den Helder, Netherlands Author
  • Erich Lienhard Centre for Metascience, Muota Institute for Future Science, Schwyz, Switzerland Author

DOI:

https://doi.org/10.5281/zenodo.22676295

Keywords:

Longevity Interventions in Model Systems; Future science and technology; Evidence synthesis; Reproducibility; Research methodology

Abstract

There is real interest in longevity interventions in model systems right now, and real uncertainty about exactly where it delivers
the most value. We pull together the current evidence for longevity interventions in model systems, covering the methodological,
practical, regulatory and cost angles, with an eye on where practice has genuinely settled and where researchers and reviewers
are still largely working it out for themselves. Selective, context-specific pursuit looks better supported by the evidence gathered
here than either broad rollout or blanket avoidance.

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Published

2023-05-20

Issue

Vol. 2 No. 1 (2023): vol 2 issue 1 2023

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