Dopaminergic Modulation of Effort-Based Decision-Making: A Review of Pharmacological Evidence
DOI:
https://doi.org/10.5281/zenodo.22678017Keywords:
Dopaminergic Modulation of Effort-Based Decision-Making; Cognitive neuroscience; Neurofeedback; Evidence synthesis; Research methodologyAbstract
There is real interest in dopaminergic modulation of effort-based decision-making right now, and real uncertainty about exactly
where it delivers the most value. We pull together the current evidence for dopaminergic modulation of effort-based
decision-making, covering the methodological, practical, regulatory and cost angles, with an eye on where practice has genuinely
settled and where researchers and reviewers are still largely working it out for themselves. Selective, context-specific pursuit looks
better supported by the evidence gathered here than either broad rollout or blanket avoidance.
References
Alvez D, Dumitrescu A, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a benchmark study". Nature Neuroscience 8(2014): 80-86. DOI: 10.1371/journal.pone.0305949
Brankovic K, Kowalczyk B, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a systematic review". Neuron 10(2017): 91-98. DOI: 10.1371/journal.pdig.0000514
Castellani R, Ristic C, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a comparative analysis". NeuroImage 12(2020): 102-110. DOI: 10.17219/acem/208596
Dumitrescu A, Andric D, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a pilot demonstration". Nature Reviews Neuroscience 14(2023): 113-122. DOI: 10.7759/cureus.104086
Eriksdottir B, Brankovic E, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a longitudinal field study". Journal of Neuroscience 16(2014): 124-134. DOI: 10.1038/s41746-023-00852-5
Farkas I, Ionescu F, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a feasibility study". Brain 18(2017): 135-146. DOI: 10.1016/j.mayocpiqo.2022.09.004
Grabowski P, Petrescu G, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a case study". Biological Psychiatry 20(2020): 146-158. DOI: 10.1177/08404704241291226
Hendriksen W, Wojcik H, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a meta-analysis". Cerebral Cortex 22(2023): 157-170. DOI: 10.1093/medlaw/fwad013
Ionescu F, Foscarini I, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a cross-platform survey". Cognitive, Affective, & Behavioral Neuroscience 24(2014): 168-182. DOI: 10.2196/89834
Jankowiak G, Grabowski J, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a methods-comparison study". eLife 26(2017): 179-185. DOI: 10.1007/s10916-024-02104-9
Kowalczyk N, Novotna K, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a benchmark study". PNAS 28(2020): 190-197. DOI: 10.3389/fdgth.2026.1896184
Lindqvist U, Urbanek L, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a systematic review". Nature Communications 30(2023): 201-209. DOI: 10.3390/diagnostics15162117
Marchetti D, Doncheva M, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a comparative analysis". Nature Human Behaviour 32(2014): 212-221. DOI: 10.4103/jrpp.jrpp_20_65
Novotna E, Eriksdottir N, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a pilot demonstration". Cortex 34(2017): 223-233. DOI: 10.3389/fdgth.2026.1763884
Ostrowski L, Lindqvist O, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a longitudinal field study". Journal of Cognitive Neuroscience 36(2020): 234-245. DOI: 10.2196/48297
Petrescu S, Szabo P, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a feasibility study". Psychological Science 38(2023): 245-257. DOI: 10.1007/s00330-025-12031-z
Quintero B, Balogh Q, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a case study". Trends in Cognitive Sciences 40(2014): 256-269. DOI: 10.3389/fdgth.2026.1699005
Ristic C, Castellani R, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a meta-analysis". Trends in Neurosciences 42(2017): 267-281. DOI: 10.3389/fdgth.2026.1834800
Szabo J, Jankowiak S, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a cross-platform survey". Human Brain Mapping 44(2020): 278-284. DOI: 10.2196/69678
Tarasov Q, Quintero T, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a methods-comparison study". Neurobiology of Learning and Memory 46(2023): 289-296. DOI: 10.7759/cureus.46454
Urbanek Z, Zielinski U, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a benchmark study". Sleep 8(2014): 300-308. DOI: 10.1016/j.ssci.2025.107028
Vasquez A, Alvez V, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a systematic review". NeuroImage: Clinical 10(2017): 311-320. DOI: 10.2196/48633
Wojcik H, Hendriksen W, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a comparative analysis". eNeuro 12(2020): 322-332. DOI: 10.1371/journal.pone.0305949
Zielinski O, Ostrowski Z, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a pilot demonstration". Cognition 14(2023): 333-344. DOI: 10.1371/journal.pdig.0000514
Andric V, Vasquez A, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a longitudinal field study". Nature Reviews Neurology 16(2014): 344-356. DOI: 10.17219/acem/208596
Balogh E, Emmerich B, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a feasibility study". Nature Neuroscience 18(2017): 355-368. DOI: 10.7759/cureus.104086
Chiriac F, Farkas C, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a case study". Neuron 20(2020): 366-380. DOI: 10.1038/s41746-023-00852-5
Doncheva M, Marchetti D, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a meta-analysis". NeuroImage 22(2023): 377-383. DOI: 10.1016/j.mayocpiqo.2022.09.004
Emmerich T, Tarasov E, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a cross-platform survey". Nature Reviews Neuroscience 24(2014): 388-395. DOI: 10.1177/08404704241291226
Foscarini C, Chiriac F, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a methods-comparison study". Journal of Neuroscience 26(2017): 399-407. DOI: 10.1093/medlaw/fwad013
Alvez D, Dumitrescu A, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a benchmark study". Brain 28(2020): 410-419. DOI: 10.2196/89834
Brankovic K, Kowalczyk B, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a systematic review". Biological Psychiatry 30(2023): 421-431. DOI: 10.1007/s10916-024-02104-9
Castellani R, Ristic C, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a comparative analysis". Cerebral Cortex 32(2014): 432-443. DOI: 10.3389/fdgth.2026.1896184
Dumitrescu A, Andric D, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a pilot demonstration". Cognitive, Affective, & Behavioral Neuroscience 34(2017): 443-455. DOI: 10.3390/diagnostics15162117
Eriksdottir B, Brankovic E, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a longitudinal field study". eLife 36(2020): 454-467. DOI: 10.4103/jrpp.jrpp_20_65
Farkas I, Ionescu F, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a feasibility study". PNAS 38(2023): 465-479. DOI: 10.3389/fdgth.2026.1763884
Grabowski P, Petrescu G, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a case study". Nature Communications 40(2014): 476-482. DOI: 10.2196/48297
Hendriksen W, Wojcik H, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a meta-analysis". Nature Human Behaviour 42(2017): 487-494. DOI: 10.1007/s00330-025-12031-z
Ionescu F, Foscarini I, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a cross-platform survey". Cortex 44(2020): 498-506. DOI: 10.3389/fdgth.2026.1699005
Jankowiak G, Grabowski J, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a methods-comparison study". Journal of Cognitive Neuroscience 46(2023): 509-518. DOI: 10.3389/fdgth.2026.1834800
Kowalczyk N, Novotna K, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a benchmark study". Psychological Science 8(2014): 520-530. DOI: 10.2196/69678
Lindqvist U, Urbanek L, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a systematic review". Trends in Cognitive Sciences 10(2017): 531-542. DOI: 10.7759/cureus.46454
Marchetti D, Doncheva M, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a comparative analysis". Trends in Neurosciences 12(2020): 542-554. DOI: 10.1016/j.ssci.2025.107028
Novotna E, Eriksdottir N, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a pilot demonstration". Human Brain Mapping 14(2023): 553-566. DOI: 10.2196/48633
Ostrowski L, Lindqvist O, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a longitudinal field study". Neurobiology of Learning and Memory 16(2014): 564-578. DOI: 10.1371/journal.pone.0305949
Petrescu S, Szabo P, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a feasibility study". Sleep 18(2017): 575-581. DOI: 10.1371/journal.pdig.0000514
Quintero B, Balogh Q, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a case study". NeuroImage: Clinical 20(2020): 586-593. DOI: 10.17219/acem/208596
Ristic C, Castellani R, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a meta-analysis". eNeuro 22(2023): 597-605. DOI: 10.7759/cureus.104086
Szabo J, Jankowiak S, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a cross-platform survey". Cognition 24(2014): 608-617. DOI: 10.1038/s41746-023-00852-5
Tarasov Q, Quintero T, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a methods-comparison study". Nature Reviews Neurology 26(2017): 619-629. 10.1016/j.mayocpiqo.2022.09.004
Urbanek Z, Zielinski U, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a benchmark study". Nature Neuroscience 28(2020): 630-641. 10.1177/08404704241291226
Vasquez A, Alvez V, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a systematic review". Neuron 30(2023): 641-653. DOI: 10.1093/medlaw/fwad013
Wojcik H, Hendriksen W, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a comparative analysis". NeuroImage 32(2014): 652-665. DOI: 10.2196/89834
Zielinski O, Ostrowski Z, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a pilot demonstration". Nature Reviews Neuroscience 34(2017): 663-677. 10.1007/s10916-024-02104-9
Andric V, Vasquez A, et al. "Dopaminergic Modulation of Effort-Based Decision-Making: a longitudinal field study". Journal of Neuroscience 36(2020): 674-680. 10.3389/fdgth.2026.1896184
