Automated Behavioural Phenotyping in Rodents: A Benchmark of Pose Estimation Against Manual Scoring

Authors

  • Fausta Andrade-Pes Department of Systems Neuroscience, Serra de Aire Institute of Cognitive Neuroscience, Porto de Mos, Portugal Author
  • Dejan-Petar Gavrilov Centre for Computational Neuroscience, Timok Institute of Cognitive Neuroscience, Zajecar, Serbia Author
  • Cecylia-M Hulewicz Centre for Comparative Cognition, Ziemia Chelminska Institute of Cognitive Neuroscience, Chelmno, Poland Author

DOI:

https://doi.org/10.5281/zenodo.22680901

Keywords:

Automated Behavioural Phenotyping in Rodents; Cognitive neuroscience; Neurofeedback; Evidence synthesis; Research methodology

Abstract

Automated Behavioural Phenotyping in Rodents has moved quickly from a niche scientific question to something a wider
community can now investigate with reasonably reliable tools, but the evidence behind it has not always kept pace. We pull
together the current evidence for automated behavioural phenotyping in rodents, covering the methodological, practical,
regulatory and cost angles, with an eye on where practice has genuinely settled and where researchers and reviewers are still
largely working it out for themselves. Selective, context-specific pursuit looks better supported by the evidence gathered here than
either broad rollout or blanket avoidance.

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Brankovic K, Kowalczyk B, et al. "Automated Behavioural Phenotyping in Rodents: a systematic review". Biological Psychiatry 30(2023): 421-431. DOI: 10.2196/69678

Castellani R, Ristic C, et al. "Automated Behavioural Phenotyping in Rodents: a comparative analysis". Cerebral Cortex 32(2014): 432-443. DOI: 10.7759/cureus.46454

Dumitrescu A, Andric D, et al. "Automated Behavioural Phenotyping in Rodents: a pilot demonstration". Cognitive, Affective, & Behavioral Neuroscience 34(2017): 443-455. DOI: 10.1016/j.ssci.2025.107028

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Farkas I, Ionescu F, et al. "Automated Behavioural Phenotyping in Rodents: a feasibility study". PNAS 38(2023): 465-479. DOI: 10.1371/journal.pone.0305949

Grabowski P, Petrescu G, et al. "Automated Behavioural Phenotyping in Rodents: a case study". Nature Communications 40(2014): 476-482. DOI: 10.1371/journal.pdig.0000514

Hendriksen W, Wojcik H, et al. "Automated Behavioural Phenotyping in Rodents: a meta-analysis". Nature Human Behaviour 42(2017): 487-494. DOI: 10.17219/acem/208596

Ionescu F, Foscarini I, et al. "Automated Behavioural Phenotyping in Rodents: a cross-platform survey". Cortex 44(2020): 498-506. DOI: 10.7759/cureus.104086

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Andric V, Vasquez A, et al. "Automated Behavioural Phenotyping in Rodents: a longitudinal field study". Journal of Neuroscience 36(2020): 674-680. DOI: 10.7759/cureus.46454

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Published

2025-04-27