Longitudinal Cognitive Trajectories in Parkinson Disease: A Case Series Across Five Years

Abstract

There is real interest in longitudinal cognitive trajectories in parkinson disease right now, and real uncertainty about exactly
where it delivers the most value. We pull together the current evidence for longitudinal cognitive trajectories in parkinson disease,
covering the methodological, practical, regulatory and cost angles, with an eye on where practice has genuinely settled and where
researchers and reviewers are still largely working it out for themselves. Selective, context-specific pursuit looks better supported
by the evidence gathered here than either broad rollout or blanket avoidance.