Patient and Public Involvement in Early Phase Design: Which Protocol Elements Actually Change
DOI:
https://doi.org/10.5281/zenodo.22649528Keywords:
Patient and Public Involvement in Early Phase Design; Translational medicine; Evidence synthesis; Clinical implementation; Health services researchAbstract
Patient and Public Involvement in Early Phase Design is an area of active development in translational medicine, with evidence
that has accumulated unevenly across its component questions. We review the current evidence base for patient and public
involvement in early phase design, spanning analytical, clinical, implementation, governance, and economic dimensions, focusing
on where practice has converged and where it continues to vary, and set out the practical considerations relevant to a service
considering its adoption. We conclude that selective, context-specific use is best supported by the evidence currently available,
rather than uniform adoption or avoidance.
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