Tissue-Engineered Grafts in Reconstructive Surgery: Manufacturing Variability and Clinical Outcome
DOI:
https://doi.org/10.5281/zenodo.22649453Keywords:
Tissue-Engineered Grafts in Reconstructive Surgery, Translational medicine; Evidence synthesis;, Clinical implementation; Health services researchAbstract
Tissue-Engineered Grafts in Reconstructive Surgery is an area of active development in translational medicine, with evidence that
has accumulated unevenly across its component questions. We review the current evidence base for tissue-engineered grafts in
reconstructive surgery, spanning analytical, clinical, implementation, governance, and economic dimensions, focusing on where
practice has converged and where it continues to vary, and set out the practical considerations relevant to a service considering
its adoption. We conclude that selective, context-specific use is best supported by the evidence currently available, rather than
uniform adoption or avoidance.
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