Long-Term Follow-Up Obligations After Integrating Vector Therapy: A Short Communication on Attrition at Five Years

Authors

  • Katarina Grubor Department of Haematology, Pomoravlje Institute of Molecular Therapeutics, Jagodina, Serbia Author
  • Constanca Malheiro Department of Cell and Gene Therapy, Beira Baixa Institute of Translational Medicine, Castelo Branco, Portugal Author
  • Marek Tammiste Centre for Real-World Evidence, Jarvamaa Institute of Translational Medicine, Paide, Estonia Author

DOI:

https://doi.org/10.5281/zenodo.22649573

Keywords:

Long-Term Follow-Up Obligations After Integrating Vector Therapy, Translational medicine; Evidence synthesis, Clinical implementation; Health services research

Abstract

Long-Term Follow-Up Obligations After Integrating Vector Therapy is an area of active development in translational medicine,
with evidence that has accumulated unevenly across its component questions. We review the current evidence base for long-term
follow-up obligations after integrating vector therapy, spanning analytical, clinical, implementation, governance, and economic
dimensions, focusing on where practice has converged and where it continues to vary, and set out the practical considerations
relevant to a service considering its adoption. We conclude that selective, context-specific use is best supported by the evidence
currently available, rather than uniform adoption or avoidance.

References

Alvez D, Dumitrescu A, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a systematic review". J Transl Med 8(2011): 80-86. DOI: 10.1016/j.ssci.2025.107028

Brankovic K, Kowalczyk B, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a methodological appraisal". Clin Pharmacol Ther 10(2014): 91-98. DOI: 10.2196/48633

Castellani R, Ristic C, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a multicentre analysis". Nat Rev Drug Discov 12(2017): 102-110. DOI: 10.1371/journal.pone.0305949

Dumitrescu A, Andric D, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a prospective cohort study". Trials 14(2020): 113-122. DOI: 10.1371/journal.pdig.0000514

Eriksdottir B, Brankovic E, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a randomised evaluation". Drug Discov Today 16(2023): 124-134. DOI: 10.17219/acem/208596

Farkas I, Ionescu F, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a consensus statement". Clin Cancer Res 18(2011): 135-146. DOI: 10.7759/cureus.104086

Grabowski P, Petrescu G, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a retrospective analysis". BMJ Open 20(2014): 146-158. DOI: 10.1038/s41746-023-00852-5

Hendriksen W, Wojcik H, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a validation study". J Clin Epidemiol 22(2017): 157-170. DOI: 10.1016/j.mayocpiqo.2022.09.004

Ionescu F, Foscarini I, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a scoping review". Contemp Clin Trials 24(2020): 168-182. DOI: 10.1177/08404704241291226

Jankowiak G, Grabowski J, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a health-economic analysis". Ther Innov Regul Sci 26(2023): 179-185. DOI: 10.1093/medlaw/fwad013

Kowalczyk N, Novotna K, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a systematic review". Br J Clin Pharmacol 28(2011): 190-197. DOI: 10.2196/89834

Lindqvist U, Urbanek L, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a methodological appraisal". PLoS Med 30(2014): 201-209. DOI: 10.1007/s10916-024-02104-9

Marchetti D, Doncheva M, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a multicentre analysis". Lancet 32(2017): 212-221. DOI: 10.3389/fdgth.2026.1896184

Novotna E, Eriksdottir N, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a prospective cohort study". N Engl J Med 34(2020): 223-233. DOI: 10.3390/diagnostics15162117

Ostrowski L, Lindqvist O, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a randomised evaluation". JAMA 36(2023): 234-245. DOI: 10.4103/jrpp.jrpp_20_65

Petrescu S, Szabo P, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a consensus statement". Nat Med 38(2011): 245-257. DOI: 10.3389/fdgth.2026.1763884

Quintero B, Balogh Q, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a retrospective analysis". Cell Rep Med 40(2014): 256-269. DOI: 10.2196/48297

Ristic C, Castellani R, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a validation study". Clin Transl Sci 42(2017): 267-281. DOI: 10.1007/s00330-025-12031-z

Szabo J, Jankowiak S, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a scoping review". Pharmacogenomics J 44(2020): 278-284. DOI: 10.3389/fdgth.2026.1699005

Tarasov Q, Quintero T, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a health-economic analysis". Regul Toxicol Pharmacol 46(2023): 289-296. DOI: 10.3389/fdgth.2026.1834800

Urbanek Z, Zielinski U, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a systematic review". Drug Saf 8(2011): 300-308. DOI: 10.2196/69678

Vasquez A, Alvez V, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a methodological appraisal". Ann Intern Med 10(2014): 311-320. DOI: 10.7759/cureus.46454

Wojcik H, Hendriksen W, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a multicentre analysis". BMC Med 12(2017): 322-332. DOI: 10.1016/j.ssci.2025.107028

Zielinski O, Ostrowski Z, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a prospective cohort study". Sci Transl Med 14(2020): 333-344. DOI: 10.2196/48633

Andric V, Vasquez A, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a randomised evaluation". J Transl Med 16(2023): 344-356. DOI: 10.1371/journal.pone.0305949

Balogh E, Emmerich B, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a consensus statement". Clin Pharmacol Ther 18(2011): 355-368. DOI: 10.1371/journal.pdig.0000514

Chiriac F, Farkas C, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a retrospective analysis". Nat Rev Drug Discov 20(2014): 366-380. DOI: 10.17219/acem/208596

Doncheva M, Marchetti D, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a validation study". Trials 22(2017): 377-383. DOI: 10.7759/cureus.104086

Emmerich T, Tarasov E, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a scoping review". Drug Discov Today 24(2020): 388-395. DOI: 10.1038/s41746-023-00852-5

Foscarini C, Chiriac F, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a health-economic analysis". Clin Cancer Res 26(2023): 399-407. DOI: 10.1016/j.mayocpiqo.2022.09.004

Alvez D, Dumitrescu A, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a systematic review". BMJ Open 28(2011): 410-419. DOI: 10.1177/08404704241291226

Brankovic K, Kowalczyk B, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a methodological appraisal". J Clin Epidemiol 30(2014): 421-431. DOI: 10.1093/medlaw/fwad013

Castellani R, Ristic C, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a multicentre analysis". Contemp Clin Trials 32(2017): 432-443. DOI: 10.2196/89834

Dumitrescu A, Andric D, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a prospective cohort study". Ther Innov Regul Sci 34(2020): 443-455. DOI: 10.1007/s10916-024-02104-9

Eriksdottir B, Brankovic E, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a randomised evaluation". Br J Clin Pharmacol 36(2023): 454-467. DOI: 10.3389/fdgth.2026.1896184

Farkas I, Ionescu F, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a consensus statement". PLoS Med 38(2011): 465-479. DOI: 10.3390/diagnostics15162117

Grabowski P, Petrescu G, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a retrospective analysis". Lancet 40(2014): 476-482. DOI: 10.4103/jrpp.jrpp_20_65

Hendriksen W, Wojcik H, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a validation study". N Engl J Med 42(2017): 487-494. DOI: 10.3389/fdgth.2026.1763884

Ionescu F, Foscarini I, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a scoping review". JAMA 44(2020): 498-506. DOI: 10.2196/48297

Jankowiak G, Grabowski J, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a health-economic analysis". Nat Med 46(2023): 509-518. DOI: 10.1007/s00330-025-12031-z

Kowalczyk N, Novotna K, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a systematic review". Cell Rep Med 8(2011): 520-530. DOI: 10.3389/fdgth.2026.1699005

Lindqvist U, Urbanek L, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a methodological appraisal". Clin Transl Sci 10(2014): 531-542. DOI: 10.3389/fdgth.2026.1834800

Marchetti D, Doncheva M, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a multicentre analysis". Pharmacogenomics J 12(2017): 542-554. DOI: 10.2196/69678

Novotna E, Eriksdottir N, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a prospective cohort study". Regul Toxicol Pharmacol 14(2020): 553-566. DOI: 10.7759/cureus.46454

Ostrowski L, Lindqvist O, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a randomised evaluation". Drug Saf 16(2023): 564-578. DOI: 10.1016/j.ssci.2025.107028

Petrescu S, Szabo P, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a consensus statement". Ann Intern Med 18(2011): 575-581. DOI: 10.2196/48633

Quintero B, Balogh Q, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a retrospective analysis". BMC Med 20(2014): 586-593. DOI: 10.1371/journal.pone.0305949

Ristic C, Castellani R, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a validation study". Sci Transl Med 22(2017): 597-605. DOI: 10.1371/journal.pdig.0000514

Szabo J, Jankowiak S, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a scoping review". J Transl Med 24(2020): 608-617. DOI: 10.17219/acem/208596

Tarasov Q, Quintero T, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a health-economic analysis". Clin Pharmacol Ther 26(2023): 619-629. DOI: 10.7759/cureus.104086

Urbanek Z, Zielinski U, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a systematic review". Nat Rev Drug Discov 28(2011): 630-641. DOI: 10.1038/s41746-023-00852-5

Vasquez A, Alvez V, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a methodological appraisal". Trials 30(2014): 641-653. DOI: 10.1016/j.mayocpiqo.2022.09.004

Wojcik H, Hendriksen W, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a multicentre analysis". Drug Discov Today 32(2017): 652-665. DOI: 10.1177/08404704241291226

Zielinski O, Ostrowski Z, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a prospective cohort study". Clin Cancer Res 34(2020): 663-677. DOI: 10.1093/medlaw/fwad013

Andric V, Vasquez A, et al. "Long-Term Follow-Up Obligations After Integrating Vector Therapy: a randomised evaluation". BMJ Open 36(2023): 674-680. DOI: 10.2196/89834

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Published

2026-05-12

Issue

Vol. 5 No. 2 (2026): vol 5 issue 2 2026

Section

Articles

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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Long-Term Follow-Up Obligations After Integrating Vector Therapy: A Short Communication on Attrition at Five Years. (2026). Translational Medicine & Therapeutics Journal, 5(2), 37-45. https://doi.org/10.5281/zenodo.22649573

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