Gene Drive Systems in Agricultural Pest Management: A Perspective on Containment and Governance

Authors

  • Dulcineia Jordao Centre for Biosafety, Charneca Centre for Plant Genome Engineering, Coruche, Portugal Author
  • Erik Adamec Department of Entomology, Turiec Institute of Agricultural Biotechnology, Martin, Slovakia Author
  • Kristin Kristmundsdottir Centre for Biotechnology Policy, Rangarvellir Centre for Plant Genome Engineering, Hella, Iceland Author

DOI:

https://doi.org/10.5281/zenodo.22666570

Keywords:

Gene Drive Systems in Agricultural Pest Management; Agricultural biotechnology; Gene editing; Evidence synthesis; Biosafety regulation

Abstract

There is real interest in gene drive systems in agricultural pest management right now, and real uncertainty about exactly where it
delivers the most value. We pull together the current evidence for gene drive systems in agricultural pest management, covering
the methodological, practical, regulatory and cost angles, with an eye on where practice has genuinely settled and where
researchers and regulators are still largely working it out for themselves. Selective, context-specific adoption looks better
supported by the evidence gathered here than either broad rollout or blanket avoidance.

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Alvez D, Dumitrescu A, et al. "Gene Drive Systems in Agricultural Pest Management: a field trial". Mol Plant 28(2020): 410-419. DOI: 10.1093/medlaw/fwad013

Brankovic K, Kowalczyk B, et al. "Gene Drive Systems in Agricultural Pest Management: a systematic review". J Exp Bot 30(2023): 421-431. DOI: 10.2196/89834

Castellani R, Ristic C, et al. "Gene Drive Systems in Agricultural Pest Management: a confined-trial evaluation". Crop Sci 32(2014): 432-443. DOI: 10.1007/s10916-024-02104-9

Dumitrescu A, Andric D, et al. "Gene Drive Systems in Agricultural Pest Management: a benchmark comparison". Agron J 34(2017): 443-455. DOI: 10.3389/fdgth.2026.1896184

Eriksdottir B, Brankovic E, et al. "Gene Drive Systems in Agricultural Pest Management: a multi-generation study". Plant Physiol 36(2020): 454-467. DOI: 10.3390/diagnostics15162117

Farkas I, Ionescu F, et al. "Gene Drive Systems in Agricultural Pest Management: a pilot deployment". New Phytol 38(2023): 465-479. DOI: 10.4103/jrpp.jrpp_20_65

Grabowski P, Petrescu G, et al. "Gene Drive Systems in Agricultural Pest Management: a case study". Nat Biotechnol 40(2014): 476-482. DOI: 10.3389/fdgth.2026.1763884

Hendriksen W, Wojcik H, et al. "Gene Drive Systems in Agricultural Pest Management: a meta-analysis". Sci Rep 42(2017): 487-494. DOI: 10.2196/48297

Ionescu F, Foscarini I, et al. "Gene Drive Systems in Agricultural Pest Management: a comparative trial". PLoS One 44(2020): 498-506. DOI: 10.1007/s00330-025-12031-z

Jankowiak G, Grabowski J, et al. "Gene Drive Systems in Agricultural Pest Management: a stakeholder-survey study". BMC Plant Biol 46(2023): 509-518. DOI: 10.3389/fdgth.2026.1699005

Kowalczyk N, Novotna K, et al. "Gene Drive Systems in Agricultural Pest Management: a field trial". Biotechnol Adv 8(2014): 520-530. DOI: 10.3389/fdgth.2026.1834800

Lindqvist U, Urbanek L, et al. "Gene Drive Systems in Agricultural Pest Management: a systematic review". Plant Mol Biol 10(2017): 531-542. DOI: 10.2196/69678

Marchetti D, Doncheva M, et al. "Gene Drive Systems in Agricultural Pest Management: a confined-trial evaluation". Field Crops Res 12(2020): 542-554. DOI: 10.7759/cureus.46454

Novotna E, Eriksdottir N, et al. "Gene Drive Systems in Agricultural Pest Management: a benchmark comparison". Euphytica 14(2023): 553-566. DOI: 10.1016/j.ssci.2025.107028

Ostrowski L, Lindqvist O, et al. "Gene Drive Systems in Agricultural Pest Management: a multi-generation study". Front Genome Ed 16(2014): 564-578. DOI: 10.2196/48633

Petrescu S, Szabo P, et al. "Gene Drive Systems in Agricultural Pest Management: a pilot deployment". CRISPR J 18(2017): 575-581. DOI: 10.1371/journal.pone.0305949

Quintero B, Balogh Q, et al. "Gene Drive Systems in Agricultural Pest Management: a case study". Plant Cell 20(2020): 586-593. DOI: 10.1371/journal.pdig.0000514

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Andric V, Vasquez A, et al. "Gene Drive Systems in Agricultural Pest Management: a multi-generation study". Mol Plant 36(2020): 674-680. DOI: 10.1007/s10916-024-02104-9

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Published

2023-10-16