Biostimulant Efficacy Claims: Systematic Review of Trial Design and Effect Size Reporting
DOI:
https://doi.org/10.5281/zenodo.22666579Keywords:
Biostimulant Efficacy Claims; Agricultural biotechnology; Gene editing; Evidence synthesis; Biosafety regulationAbstract
Biostimulant Efficacy Claims has moved quickly from a research idea to something a working breeding or production programme
can actually use, but the evidence behind it has not always kept pace. We pull together the current evidence for biostimulant
efficacy claims, covering the methodological, practical, regulatory and cost angles, with an eye on where practice has genuinely
settled and where researchers and regulators are still largely working it out for themselves. Selective, context-specific adoption
looks better supported by the evidence gathered here than either broad rollout or blanket avoidance.
References
Alvez D, Dumitrescu A, et al. "Biostimulant Efficacy Claims: a field trial". Plant Biotechnol J 8(2014): 80-86. DOI: 10.1371/journal.pone.0305949
Brankovic K, Kowalczyk B, et al. "Biostimulant Efficacy Claims: a systematic review". Theor Appl Genet 10(2017): 91-98. DOI: 10.1371/journal.pdig.0000514
Castellani R, Ristic C, et al. "Biostimulant Efficacy Claims: a confined-trial evaluation". Front Plant Sci 12(2020): 102-110. DOI: 10.17219/acem/208596
Dumitrescu A, Andric D, et al. "Biostimulant Efficacy Claims: a benchmark comparison". Transgenic Res 14(2023): 113-122. DOI: 10.7759/cureus.104086
Eriksdottir B, Brankovic E, et al. "Biostimulant Efficacy Claims: a multi-generation study". GM Crops Food 16(2014): 124-134. DOI: 10.1038/s41746-023-00852-5
Farkas I, Ionescu F, et al. "Biostimulant Efficacy Claims: a pilot deployment". Plant Cell Rep 18(2017): 135-146. DOI: 10.1016/j.mayocpiqo.2022.09.004
Grabowski P, Petrescu G, et al. "Biostimulant Efficacy Claims: a case study". Mol Plant 20(2020): 146-158. DOI: 10.1177/08404704241291226
Hendriksen W, Wojcik H, et al. "Biostimulant Efficacy Claims: a meta-analysis". J Exp Bot 22(2023): 157-170. DOI: 10.1093/medlaw/fwad013
Ionescu F, Foscarini I, et al. "Biostimulant Efficacy Claims: a comparative trial". Crop Sci 24(2014): 168-182. DOI:
2196/89834 10. Jankowiak G, Grabowski J, et al. "Biostimulant Efficacy Claims: a stakeholder-survey study". Agron J 26(2017): 179-185. DOI: 10.1007/s10916-024-02104-9
Kowalczyk N, Novotna K, et al. "Biostimulant Efficacy Claims: a field trial". Plant Physiol 28(2020): 190-197. DOI: 10.3389/fdgth.2026.1896184
Lindqvist U, Urbanek L, et al. "Biostimulant Efficacy Claims: a systematic review". New Phytol 30(2023): 201-209. DOI: 10.3390/diagnostics15162117
Marchetti D, Doncheva M, et al. "Biostimulant Efficacy Claims: a confined-trial evaluation". Nat Biotechnol 32(2014): 212-221. DOI: 10.4103/jrpp.jrpp_20_65
Novotna E, Eriksdottir N, et al. "Biostimulant Efficacy Claims: a benchmark comparison". Sci Rep 34(2017): 223-233. DOI: 10.3389/fdgth.2026.1763884
Ostrowski L, Lindqvist O, et al. "Biostimulant Efficacy Claims: a multi-generation study". PLoS One 36(2020): 234-245. DOI: 10.2196/48297
Petrescu S, Szabo P, et al. "Biostimulant Efficacy Claims: a pilot deployment". BMC Plant Biol 38(2023): 245-257. DOI: 10.1007/s00330-025-12031-z
Quintero B, Balogh Q, et al. "Biostimulant Efficacy Claims: a case study". Biotechnol Adv 40(2014): 256-269. DOI: 10.3389/fdgth.2026.1699005
Ristic C, Castellani R, et al. "Biostimulant Efficacy Claims: a meta-analysis". Plant Mol Biol 42(2017): 267-281. DOI: 10.3389/fdgth.2026.1834800
Szabo J, Jankowiak S, et al. "Biostimulant Efficacy Claims: a comparative trial". Field Crops Res 44(2020): 278-284. DOI: 10.2196/69678
Tarasov Q, Quintero T, et al. "Biostimulant Efficacy Claims: a stakeholder-survey study". Euphytica 46(2023): 289-296. DOI: 10.7759/cureus.46454
Urbanek Z, Zielinski U, et al. "Biostimulant Efficacy Claims: a field trial". Front Genome Ed 8(2014): 300-308. DOI: 10.1016/j.ssci.2025.107028
Vasquez A, Alvez V, et al. "Biostimulant Efficacy Claims: a systematic review". CRISPR J 10(2017): 311-320. DOI: 10.2196/48633
Wojcik H, Hendriksen W, et al. "Biostimulant Efficacy Claims: a confined-trial evaluation". Plant Cell 12(2020): 322-332. DOI: 10.1371/journal.pone.0305949
Zielinski O, Ostrowski Z, et al. "Biostimulant Efficacy Claims: a benchmark comparison". Trends Biotechnol 14(2023): 333-344. DOI: 10.1371/journal.pdig.0000514
Andric V, Vasquez A, et al. "Biostimulant Efficacy Claims: a multi-generation study". Plant Biotechnol J 16(2014): 344-356. DOI: 10.17219/acem/208596
Balogh E, Emmerich B, et al. "Biostimulant Efficacy Claims: a pilot deployment". Theor Appl Genet 18(2017): 355-368. DOI: 10.7759/cureus.104086
Chiriac F, Farkas C, et al. "Biostimulant Efficacy Claims: a case study". Front Plant Sci 20(2020): 366-380. DOI: 10.1038/s41746-023-00852-5
Doncheva M, Marchetti D, et al. "Biostimulant Efficacy Claims: a meta-analysis". Transgenic Res 22(2023): 377-383. DOI: 10.1016/j.mayocpiqo.2022.09.004
Emmerich T, Tarasov E, et al. "Biostimulant Efficacy Claims: a comparative trial". GM Crops Food 24(2014): 388-395. DOI: 10.1177/08404704241291226
Foscarini C, Chiriac F, et al. "Biostimulant Efficacy Claims: a stakeholder-survey study". Plant Cell Rep 26(2017): 399-407. DOI: 10.1093/medlaw/fwad013
Alvez D, Dumitrescu A, et al. "Biostimulant Efficacy Claims: a field trial". Mol Plant 28(2020): 410-419. DOI: 10.2196/89834
Brankovic K, Kowalczyk B, et al. "Biostimulant Efficacy Claims: a systematic review". J Exp Bot 30(2023): 421-431. DOI: 10.1007/s10916-024-02104-9
Castellani R, Ristic C, et al. "Biostimulant Efficacy Claims: a confined-trial evaluation". Crop Sci 32(2014): 432-443. DOI: 10.3389/fdgth.2026.1896184
Dumitrescu A, Andric D, et al. "Biostimulant Efficacy Claims: a benchmark comparison". Agron J 34(2017): 443-455. DOI: 10.3390/diagnostics15162117
Eriksdottir B, Brankovic E, et al. "Biostimulant Efficacy Claims: a multi-generation study". Plant Physiol 36(2020): 454-467. DOI: 10.4103/jrpp.jrpp_20_65
Farkas I, Ionescu F, et al. "Biostimulant Efficacy Claims: a pilot deployment". New Phytol 38(2023): 465-479. DOI: 10.3389/fdgth.2026.1763884
Grabowski P, Petrescu G, et al. "Biostimulant Efficacy Claims: a case study". Nat Biotechnol 40(2014): 476-482. DOI: 10.2196/48297
Hendriksen W, Wojcik H, et al. "Biostimulant Efficacy Claims: a meta-analysis". Sci Rep 42(2017): 487-494. DOI: 10.1007/s00330-025-12031-z
Ionescu F, Foscarini I, et al. "Biostimulant Efficacy Claims: a comparative trial". PLoS One 44(2020): 498-506. DOI: 10.3389/fdgth.2026.1699005
Jankowiak G, Grabowski J, et al. "Biostimulant Efficacy Claims: a stakeholder-survey study". BMC Plant Biol 46(2023): 509-518. DOI: 10.3389/fdgth.2026.1834800
Kowalczyk N, Novotna K, et al. "Biostimulant Efficacy Claims: a field trial". Biotechnol Adv 8(2014): 520-530. DOI: 10.2196/69678
Lindqvist U, Urbanek L, et al. "Biostimulant Efficacy Claims: a systematic review". Plant Mol Biol 10(2017): 531-542. DOI: 10.7759/cureus.46454
Marchetti D, Doncheva M, et al. "Biostimulant Efficacy Claims: a confined-trial evaluation". Field Crops Res 12(2020): 542-554. DOI: 10.1016/j.ssci.2025.107028
Novotna E, Eriksdottir N, et al. "Biostimulant Efficacy Claims: a benchmark comparison". Euphytica 14(2023): 553-566. DOI: 10.2196/48633
Ostrowski L, Lindqvist O, et al. "Biostimulant Efficacy Claims: a multi-generation study". Front Genome Ed 16(2014): 564-578. DOI: 10.1371/journal.pone.0305949
Petrescu S, Szabo P, et al. "Biostimulant Efficacy Claims: a pilot deployment". CRISPR J 18(2017): 575-581. DOI: 10.1371/journal.pdig.0000514
Quintero B, Balogh Q, et al. "Biostimulant Efficacy Claims: a case study". Plant Cell 20(2020): 586-593. DOI: 10.17219/acem/208596
Ristic C, Castellani R, et al. "Biostimulant Efficacy Claims: a meta-analysis". Trends Biotechnol 22(2023): 597-605. DOI: 10.7759/cureus.104086
Szabo J, Jankowiak S, et al. "Biostimulant Efficacy Claims: a comparative trial". Plant Biotechnol J 24(2014): 608-617. DOI: 10.1038/s41746-023-00852-5
Tarasov Q, Quintero T, et al. "Biostimulant Efficacy Claims: a stakeholder-survey study". Theor Appl Genet 26(2017): 619-629. DOI: 10.1016/j.mayocpiqo.2022.09.004
Urbanek Z, Zielinski U, et al. "Biostimulant Efficacy Claims: a field trial". Front Plant Sci 28(2020): 630-641. DOI: 10.1177/08404704241291226
Vasquez A, Alvez V, et al. "Biostimulant Efficacy Claims: a systematic review". Transgenic Res 30(2023): 641-653. DOI: 10.1093/medlaw/fwad013
Wojcik H, Hendriksen W, et al. "Biostimulant Efficacy Claims: a confined-trial evaluation". GM Crops Food 32(2014): 652-665. DOI: 10.2196/89834
Zielinski O, Ostrowski Z, et al. "Biostimulant Efficacy Claims: a benchmark comparison". Plant Cell Rep 34(2017): 663-677. DOI: 10.1007/s10916-024-02104-9
Andric V, Vasquez A, et al. "Biostimulant Efficacy Claims: a multi-generation study". Mol Plant 36(2020): 674-680. DOI: 10.3389/fdgth.2026.1896184

