Metabolomic Signatures of Nitrogen Stress in Maize: A Dataset Across Six Genotypes and Four Regimes

Authors

  • Fulvia Donadoni Centre for Metabolomics, Murgia Institute of Agricultural Biotechnology, Altamura, Italy Author
  • Birthe Hovgaard Department of Plant Physiology, Odsherred Institute of Agricultural Biotechnology, Nykobing Sjaelland, Denmark Author
  • Jaroslava Gabriel-Hou Department of Bioinformatics, Kokorinsko Centre for Plant Genome Engineering, Melnik, Czech Republic Author

DOI:

https://doi.org/10.5281/zenodo.22666651

Keywords:

Metabolomic Signatures of Nitrogen Stress in Maize; Agricultural biotechnology; Gene editing; Evidence synthesis; Biosafety regulation

Abstract

Metabolomic Signatures of Nitrogen Stress in Maize has moved quickly from a research idea to something a working breeding or
production programme can actually use, but the evidence behind it has not always kept pace. We pull together the current
evidence for metabolomic signatures of nitrogen stress in maize, covering the methodological, practical, regulatory and cost
angles, with an eye on where practice has genuinely settled and where researchers and regulators are still largely working it out
for themselves. Selective, context-specific adoption looks better supported by the evidence gathered here than either broad rollout
or blanket avoidance.

References

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Foscarini C, Chiriac F, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a stakeholder-survey study". Plant Cell Rep 26(2017): 399-407. DOI: 10.4103/jrpp.jrpp_20_65

Alvez D, Dumitrescu A, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a field trial". Mol Plant 28(2020): 410-419. DOI: 10.3389/fdgth.2026.1763884

Brankovic K, Kowalczyk B, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a systematic review". J Exp Bot 30(2023): 421-431. DOI: 10.2196/48297

Castellani R, Ristic C, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a confined-trial evaluation". Crop Sci 32(2014): 432-443. DOI: 10.1007/s00330-025-12031-z

Dumitrescu A, Andric D, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a benchmark comparison". Agron J 34(2017): 443-455. DOI: 10.3389/fdgth.2026.1699005

Eriksdottir B, Brankovic E, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a multi-generation study". Plant Physiol 36(2020): 454-467. DOI: 10.3389/fdgth.2026.1834800

Farkas I, Ionescu F, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a pilot deployment". New Phytol 38(2023): 465-479. DOI: 10.2196/69678

Grabowski P, Petrescu G, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a case study". Nat Biotechnol 40(2014): 476-482. DOI: 10.7759/cureus.46454

Hendriksen W, Wojcik H, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a meta-analysis". Sci Rep 42(2017): 487-494. DOI: 10.1016/j.ssci.2025.107028

Ionescu F, Foscarini I, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a comparative trial". PLoS One 44(2020): 498-506. DOI: 10.2196/48633

Jankowiak G, Grabowski J, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a stakeholder-survey study". BMC Plant Biol 46(2023): 509-518. DOI: 10.1371/journal.pone.0305949

Kowalczyk N, Novotna K, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a field trial". Biotechnol Adv 8(2014): 520-530. DOI: 10.1371/journal.pdig.0000514

Lindqvist U, Urbanek L, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a systematic review". Plant Mol Biol 10(2017): 531-542. DOI: 10.17219/acem/208596

Marchetti D, Doncheva M, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a confined-trial evaluation". Field Crops Res 12(2020): 542-554. DOI: 10.7759/cureus.104086

Novotna E, Eriksdottir N, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a benchmark comparison". Euphytica 14(2023): 553-566. DOI: 10.1038/s41746-023-00852-5

Ostrowski L, Lindqvist O, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a multi-generation study". Front Genome Ed 16(2014): 564-578. DOI: 10.1016/j.mayocpiqo.2022.09.004

Petrescu S, Szabo P, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a pilot deployment". CRISPR J 18(2017): 575-581. DOI: 10.1177/08404704241291226

Quintero B, Balogh Q, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a case study". Plant Cell 20(2020): 586-593. DOI: 10.1093/medlaw/fwad013

Ristic C, Castellani R, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a meta-analysis". Trends Biotechnol 22(2023): 597-605. DOI: 10.2196/89834

Szabo J, Jankowiak S, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a comparative trial". Plant Biotechnol J 24(2014): 608-617. DOI: 10.1007/s10916-024-02104-9

Tarasov Q, Quintero T, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a stakeholder-survey study". Theor Appl Genet 26(2017): 619-629. DOI: 10.3389/fdgth.2026.1896184

Urbanek Z, Zielinski U, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a field trial". Front Plant Sci 28(2020): 630-641. DOI: 10.3390/diagnostics15162117

Vasquez A, Alvez V, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a systematic review". Transgenic Res 30(2023): 641-653. DOI: 10.4103/jrpp.jrpp_20_65

Wojcik H, Hendriksen W, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a confined-trial evaluation". GM Crops Food 32(2014): 652-665. DOI: 10.3389/fdgth.2026.1763884

Zielinski O, Ostrowski Z, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a benchmark comparison". Plant Cell Rep 34(2017): 663-677. DOI: 10.2196/48297

Andric V, Vasquez A, et al. "Metabolomic Signatures of Nitrogen Stress in Maize: a multi-generation study". Mol Plant 36(2020): 674-680. DOI: 10.1007/s00330-025-12031-z

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Published

2024-06-26