Genome Editing in Vegetatively Propagated Crops: A Benchmark of Delivery Methods Without Transgenes
DOI:
https://doi.org/10.5281/zenodo.22666862Keywords:
Genome Editing in Vegetatively Propagated Crops; Agricultural biotechnology; Gene editing; Evidence synthesis; Biosafety regulationAbstract
There is real interest in genome editing in vegetatively propagated crops right now, and real uncertainty about exactly where it
delivers the most value. We pull together the current evidence for genome editing in vegetatively propagated crops, covering the
methodological, practical, regulatory and cost angles, with an eye on where practice has genuinely settled and where researchers
and regulators are still largely working it out for themselves. Selective, context-specific adoption looks better supported by the
evidence gathered here than either broad rollout or blanket avoidance.
References
Alvez D, Dumitrescu A, et al. "Genome Editing in Vegetatively Propagated Crops: a field trial". Plant Biotechnol J 8(2014): 80-86. DOI: 10.7759/cureus.46454
Brankovic K, Kowalczyk B, et al. "Genome Editing in Vegetatively Propagated Crops: a systematic review". Theor Appl Genet 10(2017): 91-98. DOI: 10.1016/j.ssci.2025.107028
Castellani R, Ristic C, et al. "Genome Editing in Vegetatively Propagated Crops: a confined-trial evaluation". Front Plant Sci 12(2020): 102-110. DOI: 10.2196/48633
Dumitrescu A, Andric D, et al. "Genome Editing in Vegetatively Propagated Crops: a benchmark comparison". Transgenic Res 14(2023): 113-122. DOI: 10.1371/journal.pone.0305949
Eriksdottir B, Brankovic E, et al. "Genome Editing in Vegetatively Propagated Crops: a multi-generation study". GM Crops Food 16(2014): 124-134. DOI: 10.1371/journal.pdig.0000514
Farkas I, Ionescu F, et al. "Genome Editing in Vegetatively Propagated Crops: a pilot deployment". Plant Cell Rep 18(2017): 135-146. DOI: 10.17219/acem/208596
Grabowski P, Petrescu G, et al. "Genome Editing in Vegetatively Propagated Crops: a case study". Mol Plant 20(2020): 146-158. DOI: 10.7759/cureus.104086
Hendriksen W, Wojcik H, et al. "Genome Editing in Vegetatively Propagated Crops: a meta-analysis". J Exp Bot 22(2023): 157-170. DOI: 10.1038/s41746-023-00852-5
Ionescu F, Foscarini I, et al. "Genome Editing in Vegetatively Propagated Crops: a comparative trial". Crop Sci 24(2014): 168-182. DOI: 10.1016/j.mayocpiqo.2022.09.004
Jankowiak G, Grabowski J, et al. "Genome Editing in Vegetatively Propagated Crops: a stakeholder-survey study". Agron J 26(2017): 179-185. DOI: 10.1177/08404704241291226
Kowalczyk N, Novotna K, et al. "Genome Editing in Vegetatively Propagated Crops: a field trial". Plant Physiol 28(2020): 190-197. DOI: 10.1093/medlaw/fwad013
Lindqvist U, Urbanek L, et al. "Genome Editing in Vegetatively Propagated Crops: a systematic review". New Phytol 30(2023): 201-209. DOI: 10.2196/89834
Marchetti D, Doncheva M, et al. "Genome Editing in Vegetatively Propagated Crops: a confined-trial evaluation". Nat Biotechnol 32(2014): 212-221. DOI: 10.1007/s10916-024-02104-9
Novotna E, Eriksdottir N, et al. "Genome Editing in Vegetatively Propagated Crops: a benchmark comparison". Sci Rep 34(2017): 223-233. DOI: 10.3389/fdgth.2026.1896184
Ostrowski L, Lindqvist O, et al. "Genome Editing in Vegetatively Propagated Crops: a multi-generation study". PLoS One 36(2020): 234-245. DOI: 10.3390/diagnostics15162117
Petrescu S, Szabo P, et al. "Genome Editing in Vegetatively Propagated Crops: a pilot deployment". BMC Plant Biol 38(2023): 245-257. DOI: 10.4103/jrpp.jrpp_20_65
Quintero B, Balogh Q, et al. "Genome Editing in Vegetatively Propagated Crops: a case study". Biotechnol Adv 40(2014): 256-269. DOI: 10.3389/fdgth.2026.1763884
Ristic C, Castellani R, et al. "Genome Editing in Vegetatively Propagated Crops: a meta-analysis". Plant Mol Biol 42(2017): 267-281. DOI: 10.2196/48297
Szabo J, Jankowiak S, et al. "Genome Editing in Vegetatively Propagated Crops: a comparative trial". Field Crops Res 44(2020): 278-284. DOI: 10.1007/s00330-025-12031-z
Tarasov Q, Quintero T, et al. "Genome Editing in Vegetatively Propagated Crops: a stakeholder-survey study". Euphytica 46(2023): 289-296. DOI: 10.3389/fdgth.2026.1699005
Urbanek Z, Zielinski U, et al. "Genome Editing in Vegetatively Propagated Crops: a field trial". Front Genome Ed 8(2014): 300-308. DOI: 10.3389/fdgth.2026.1834800
Vasquez A, Alvez V, et al. "Genome Editing in Vegetatively Propagated Crops: a systematic review". CRISPR J 10(2017): 311-320. DOI: 10.2196/69678
Wojcik H, Hendriksen W, et al. "Genome Editing in Vegetatively Propagated Crops: a confined-trial evaluation". Plant Cell 12(2020): 322-332. DOI: 10.7759/cureus.46454
Zielinski O, Ostrowski Z, et al. "Genome Editing in Vegetatively Propagated Crops: a benchmark comparison". Trends Biotechnol 14(2023): 333-344. DOI: 10.1016/j.ssci.2025.107028
Andric V, Vasquez A, et al. "Genome Editing in Vegetatively Propagated Crops: a multi-generation study". Plant Biotechnol J 16(2014): 344-356. DOI: 10.2196/48633
Balogh E, Emmerich B, et al. "Genome Editing in Vegetatively Propagated Crops: a pilot deployment". Theor Appl Genet 18(2017): 355-368. DOI: 10.1371/journal.pone.0305949
Chiriac F, Farkas C, et al. "Genome Editing in Vegetatively Propagated Crops: a case study". Front Plant Sci 20(2020): 366-380. DOI: 10.1371/journal.pdig.0000514
Doncheva M, Marchetti D, et al. "Genome Editing in Vegetatively Propagated Crops: a meta-analysis". Transgenic Res 22(2023): 377-383. DOI: 10.17219/acem/208596
Emmerich T, Tarasov E, et al. "Genome Editing in Vegetatively Propagated Crops: a comparative trial". GM Crops Food 24(2014): 388-395. DOI: 10.7759/cureus.104086
Foscarini C, Chiriac F, et al. "Genome Editing in Vegetatively Propagated Crops: a stakeholder-survey study". Plant Cell Rep 26(2017): 399-407. DOI: 10.1038/s41746-023-00852-5
Alvez D, Dumitrescu A, et al. "Genome Editing in Vegetatively Propagated Crops: a field trial". Mol Plant 28(2020): 410-419. DOI: 10.1016/j.mayocpiqo.2022.09.004
Brankovic K, Kowalczyk B, et al. "Genome Editing in Vegetatively Propagated Crops: a systematic review". J Exp Bot 30(2023): 421-431. DOI: 10.1177/08404704241291226
Castellani R, Ristic C, et al. "Genome Editing in Vegetatively Propagated Crops: a confined-trial evaluation". Crop Sci 32(2014): 432-443. DOI: 10.1093/medlaw/fwad013
Dumitrescu A, Andric D, et al. "Genome Editing in Vegetatively Propagated Crops: a benchmark comparison". Agron J 34(2017): 443-455. DOI: 10.2196/89834
Eriksdottir B, Brankovic E, et al. "Genome Editing in Vegetatively Propagated Crops: a multi-generation study". Plant Physiol 36(2020): 454-467. DOI: 10.1007/s10916-024-02104-9
Farkas I, Ionescu F, et al. "Genome Editing in Vegetatively Propagated Crops: a pilot deployment". New Phytol 38(2023): 465-479. DOI: 10.3389/fdgth.2026.1896184
Grabowski P, Petrescu G, et al. "Genome Editing in Vegetatively Propagated Crops: a case study". Nat Biotechnol 40(2014): 476-482. DOI: 10.3390/diagnostics15162117
Hendriksen W, Wojcik H, et al. "Genome Editing in Vegetatively Propagated Crops: a meta-analysis". Sci Rep 42(2017): 487-494. DOI: 10.4103/jrpp.jrpp_20_65
Ionescu F, Foscarini I, et al. "Genome Editing in Vegetatively Propagated Crops: a comparative trial". PLoS One 44(2020): 498-506. DOI: 10.3389/fdgth.2026.1763884
Jankowiak G, Grabowski J, et al. "Genome Editing in Vegetatively Propagated Crops: a stakeholder-survey study". BMC Plant Biol 46(2023): 509-518. DOI: 10.2196/48297
Kowalczyk N, Novotna K, et al. "Genome Editing in Vegetatively Propagated Crops: a field trial". Biotechnol Adv 8(2014): 520-530. DOI: 10.1007/s00330-025-12031-z
Lindqvist U, Urbanek L, et al. "Genome Editing in Vegetatively Propagated Crops: a systematic review". Plant Mol Biol 10(2017): 531-542. DOI: 10.3389/fdgth.2026.1699005
Marchetti D, Doncheva M, et al. "Genome Editing in Vegetatively Propagated Crops: a confined-trial evaluation". Field Crops Res 12(2020): 542-554. DOI: 10.3389/fdgth.2026.1834800
Novotna E, Eriksdottir N, et al. "Genome Editing in Vegetatively Propagated Crops: a benchmark comparison". Euphytica 14(2023): 553-566. DOI: 10.2196/69678
Ostrowski L, Lindqvist O, et al. "Genome Editing in Vegetatively Propagated Crops: a multi-generation study". Front Genome Ed 16(2014): 564-578. DOI: 10.7759/cureus.46454
Petrescu S, Szabo P, et al. "Genome Editing in Vegetatively Propagated Crops: a pilot deployment". CRISPR J 18(2017): 575-581. DOI: 10.1016/j.ssci.2025.107028
Quintero B, Balogh Q, et al. "Genome Editing in Vegetatively Propagated Crops: a case study". Plant Cell 20(2020): 586-593. DOI: 10.2196/48633
Ristic C, Castellani R, et al. "Genome Editing in Vegetatively Propagated Crops: a meta-analysis". Trends Biotechnol 22(2023): 597-605. DOI: 10.1371/journal.pone.0305949
Szabo J, Jankowiak S, et al. "Genome Editing in Vegetatively Propagated Crops: a comparative trial". Plant Biotechnol J 24(2014): 608-617. DOI: 10.1371/journal.pdig.0000514
Tarasov Q, Quintero T, et al. "Genome Editing in Vegetatively Propagated Crops: a stakeholder-survey study". Theor Appl Genet 26(2017): 619-629. DOI: 10.17219/acem/208596
Urbanek Z, Zielinski U, et al. "Genome Editing in Vegetatively Propagated Crops: a field trial". Front Plant Sci 28(2020): 630-641. DOI: 10.7759/cureus.104086
Vasquez A, Alvez V, et al. "Genome Editing in Vegetatively Propagated Crops: a systematic review". Transgenic Res 30(2023): 641-653. DOI: 10.1038/s41746-023-00852-5
Wojcik H, Hendriksen W, et al. "Genome Editing in Vegetatively Propagated Crops: a confined-trial evaluation". GM Crops Food 32(2014): 652-665. DOI: 10.1016/j.mayocpiqo.2022.09.004
Zielinski O, Ostrowski Z, et al. "Genome Editing in Vegetatively Propagated Crops: a benchmark comparison". Plant Cell Rep 34(2017): 663-677. DOI: 10.1177/08404704241291226
Andric V, Vasquez A, et al. "Genome Editing in Vegetatively Propagated Crops: a multi-generation study". Mol Plant 36(2020): 674-680. DOI: 10.1093/medlaw/fwad013

